Repair Kinetics of DNA Double Strand Breaks Induced by Simulated Space Radiation
نویسندگان
چکیده
منابع مشابه
[Repair of ionizing radiation induced DNA double strand breaks].
DNA double-strand breaks (DSB) are created by ionizing radiation, an important environmental genotoxic agent. DSB are repaired by two mechanisms associated with recombination. In eukaryotic cells homologous recombination depends on genes belonging to the RAD52 epistatic group. Alternative pathway, DNA end-joining in non-homologous recombination involves DNA-dependent protein kinase (DNA-PK).
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ژورنال
عنوان ژورنال: Life
سال: 2020
ISSN: 2075-1729
DOI: 10.3390/life10120341